Clinical
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Researchers Affirm Effectiveness of Two-dose HPV Vaccine
Investigators have published clinical evidence that supports the CDC’s recent recommendation for a two-dose human papillomavirus vaccine to prevent genital warts, showing that the two-dose vaccine provides the same level of protection as three doses.
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Analysis: One in Six Teen Births in 2015 Was a Repeat Birth
Most adolescent mothers take steps to prevent another pregnancy, but data indicate one in three is using a least-effective contraceptive method or no contraception at all.
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Dual-purpose Vaginal Ring Moves to Clinical Trial
Study will assess ring’s safety and pharmacokinetics in two U.S. centers.
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Anaphylaxis: An Underrecognized Killer
Prompt diagnosis and treatment improve outcomes
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Atypical Transient Symptoms Require Aggressive Investigation for Cause
Atypical transient symptoms, such as partial sensory deficit, dysarthria, vertigo and unsteadiness, unusual visual deficits, and diplopia, usually are not classified as transient ischemic attacks, and they frequently are not investigated in the same fashion. However, one-year risk of recurrent major vascular events was not significantly different between patients who had typical TIA symptoms or atypical isolated or non-isolated symptoms. Therefore, these patients should be investigated intensively in a manner similar to patients with classical TIA symptoms.
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What Is the Risk of Hemorrhage During Pregnancy for a Woman with Brain Arteriovenous Malformation?
The risk of hemorrhage in a pregnant woman with a brain arteriovenous malformation (AVM) is uncertain and management is controversial.
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Deep Brain Stimulation May Offer Hope in Treating Post-stroke Pain
This trial of deep brain stimulation of the ventral striatum/anterior limb of the internal capsule improved several measures of the affective sphere of pain in those suffering from post-stroke pain, despite no significant improvement seen in the pain disability index.
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Migraine and the Blood-brain Barrier
During spontaneous attacks of migraine with visual aura, magnetic imaging studies indicate that the blood-brain barrier remains intact and the pons is activated.
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Omega-3 Polyunsaturated Fatty Acid Supplementation and Cognitive Decline
In a randomized, placebo-controlled trial of 1,680 participants aged 70 years or older, there was no significant difference in cognitive decline between any of the intervention groups taking omega-3 polyunsaturated fatty acid supplementation and/or multidomain intervention (physical activity, cognitive training, and nutritional advice) compared to the placebo group. However, exploratory post hoc analyses showed some promise for a protective effect with intervention in certain at-risk subgroups.
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Distinguishing the Neuropathy Associated with MGUS from POEMS
Nerve conduction and electromyography can help differentiate the neuropathy associated with monoclonal gammopathy of undetermined significance (MGUS) from polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS).