Clinical
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Cardiovascular Benefits of Pharmacotherapies for Type 2 Diabetes
The most recent American Diabetes Association 2018 guidance for pharmacotherapy of type 2 diabetes mellitus suggests that for patients with existing cardiovascular (CV) disease who are uncontrolled on metformin and lifestyle, consideration should be given to prioritizing agents demonstrated to provide CV risk reduction (empagliflozin, liraglutide, and canagliflozin).
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Postprandial Glucose Excursions in Type 2 Diabetes
The most recent American Diabetes Association 2018 guidelines suggest that for persons with established cardiovascular disease who have not attained glucose goals, incorporation of agents that have shown cardiovascular risk reduction (i.e., canagliflozin, empagliflozin, liraglutide) should be a priority.
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Biomarkers for Tight Control of Crohn’s Disease
The authors suggested that treatment escalation based on the combination of clinical symptoms with biomarkers produces more favorable outcomes.
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Long-term Outcomes for Obesity
The evidence of the advantages of bariatric surgery over medical management continues to accrue.
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Anything Other Than RBBB?
The ECG in the figure was obtained from a 60-year-old woman who presented to the ED with new-onset chest pain. The initial emergency care provider interpreted this tracing as showing complete right bundle branch block. Do you agree?
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Clinical Briefs
In this section: treating COPD with statins, tackling hearing loss with greater urgency, and educating patients about malignant melanomas. -
Insulin Lispro Injection (Admelog)
Admelog is indicated to improve glycemic control in adults and pediatric patients ≥ 3 years of age with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.
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Clostridium difficile Recurrence by Orally Administered Fecal Microbiota Transplantation
Fecal microbiota transplantation orally administered in capsules was non-inferior to administration by colonoscopy.
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Blockade of CGRP for Migraine Prevention: Promising, but Not a Cure
Blockade of calcitonin gene-related peptide in patients with chronic or episodic migraine results in the prevention of about two headache days a month compared to placebo.
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Obesity Is a Hormonal Illness
Once obese, a patient’s metabolism adapts with insulin resistance to maintain body fat. High insulin levels promote fat storage and block fat burning.