Clinical
RSSArticles
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FDA Actions
In this section: Agency approves new diabetes treatment, green lights medicine for treatment of shock, gives the go ahead to a follow-on version of insulin lispro injection, launches a new website to assist with antibiotic selection, and removes a boxed warning from long-acting beta-agonists in combination with inhaled corticosteroids regarding asthma-related death.
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No Association Between Vitamin D, Calcium Supplements and Fracture Prevention in Older Adults
There were no significant associations between calcium, vitamin D, or combined calcium and vitamin D supplements or the incidence of nonvertebral, vertebral, or total fractures. The results were consistent regardless of the dose of vitamin D or calcium, sex, fracture history, dietary calcium intake, or baseline serum 25-hydroxyvitamin D concentration.
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Is There a Connection Between Breast Cancer and Hormonal Contraceptives?
In a recent study, the authors concluded that while the risk is small, there was a higher risk of breast cancer among women who currently or recently used contemporary hormonal contraceptives than among women who had never used hormonal contraceptives.
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The Sticky Wicket of Androgen Receptor Modulators
In a recent investigation, less than half the products tested contained the amount of active product claimed on the label, almost 20% contained none of the claimed active component, and some contained substances banned by the World Anti-Doping Agency.
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Addressing Insomnia
If cognitive behavioral therapy is insufficient to remedy insomnia, sedative-hypnotic agents must be added sometimes. Consultation with a sleep expert for refractory cases, or for cases requiring more sustained use of medications, is fully appropriate.
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Updated Hypertension Guidelines
Perhaps the most novel innovation is the recategorization of systolic blood pressure 130-139 mmHg or diastolic blood pressure 80-89 mmHg as stage 1 hypertension. Previously, this blood pressure zone was labeled prehypertension.
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Statins for COPD?
Even though numerous pharmacologic treatments are available to mollify COPD symptoms, mortality and disease progression do not appear to be altered by pharmacologic treatment.
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Educating Patients About ‘Ugly Duckling Sign’
Patients or their partners detect most malignant melanomas first. Enhancing public awareness of malignant melanomas and enabling patients to promptly and accurately identify at-risk lesions is important.
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An Overlooked Disability Burden
The sudden loss of hearing is considered an otologic emergency, requiring prompt evaluation. Only a few patients with identified hearing loss take advantage of hearing aids, perhaps daunted by issues like cost, potential stigma associated with wearing a hearing-assistive device, or comfort.
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How Many Conduction Defects?
The ECG and long lead II rhythm strip in the figure with the article was obtained from a 58-year-old man who was admitted to the hospital with chest pain and weakness. How would you interpret the tracing? How many different types of conduction disturbances can you identify?