Clinical
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CABG vs. PCI in Diabetes With Multivessel Coronary Artery Disease and LV Dysfunction
A propensity score-matching analysis of all patients undergoing coronary angiography in Alberta, Canada, identified a subgroup with diabetes, multivessel coronary artery disease, and left ventricular ejection fraction < 50% who were undergoing revascularization and could be separated into a group undergoing percutaneous coronary intervention (PCI) and another coronary artery bypass grafting (CABG). At five years' follow-up, the CABG group experienced significantly fewer major cardiac or cerebral vascular events compared to PCI and a low risk of stroke that was similar to that observed with PCI.
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TAVR in Lower-risk Patients: How Low Should We Go?
A meta-analysis of studies comparing transcatheter aortic valve replacement (TAVR) to surgical aortic valve replacement over a two-year follow-up in low surgical risk patients exhibits a higher mortality in the TAVR group, prompting the authors to recommend caution in applying TAVR to low-risk patients until randomized trials are completed.
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Clinical Briefs
In this section: improving cardiovascular outcomes in type 2 diabetes patients; digging deeper into penicillin allergies; and treating osteoporosis.
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Apalutamide Tablets (Erleada)
Apalutamide is indicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer.
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Providers Facilitate Transmission of Resistant Organisms
A closer look at the role providers play in the transmission of carbapenem-resistant Enterobacteriaceae.
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Physician Burnout: A Multi-specialty Perspective
Although different specialties address the problem of physician burnout, studies suggest the most effect is gained from organizational interventions.
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Another Reason to Get the Flu Shot Every Year
In a case-control study, among older adults, repeated vaccination for influenza was twice as effective in preventing severe influenza compared to non-severe influenza in patients who were admitted to the hospital.
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The Latest in Genetic Screening for Gynecologic Malignancies
Genetic testing is changing rapidly. With the advent of more sophisticated genetic mutation panels, it is important that providers of women’s healthcare consider appropriate referral and testing for those women at increased risk of malignancy.
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Breast MRI Exams Increase the Biopsy Rate Without Improving Cancer Detection
Compared to women who undergo breast cancer screening with mammography alone, those receiving MRI exams experience a two- to fivefold increased rate of core and surgical biopsy. However, the biopsies have a lower cancer yield rate than mammography alone.
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Obesity and Prolapse: Are They Related?
Women with a body mass index in the overweight and obese range are more likely to experience pelvic organ prolapse compared to women in the normal range.