Clinical
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Tuberculosis in the United States in 2017
While the incidence of tuberculosis in the United States in 2017 was the lowest ever recorded, the current rate of decline would be required to almost double to reach the goal of elimination of the disease in this country by the year 2100.
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Extended-pulsed Dosing of Fidaxomicin vs. Standard-dose Vancomycin for Clostridium difficile Infection
A randomized, controlled, open-label clinical trial conducted at 86 European hospitals that included adults aged 60 years or older found that extended-pulsed dosing of fidaxomicin was superior to standard-dose vancomycin for sustained cure of Clostridium difficile infection and resulted in fewer disease recurrences.
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Dealing With Multidrug-resistant Organisms on a National Level: CDC Successes and Problems on the Horizon
CDC efforts, implemented at the local level, have been associated with a modest reduction in the incidences of Escherichia coli and Klebsiella pneumoniae with an ESBL phenotype and a more dramatic reduction in carbapenem-resistant Enterobacteriaceae.
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Planes, Pathogens, and Passengers: Infection Risk During Commercial Air Travel
Although air travel has been linked to transmission of respiratory infections, the actual risk of becoming infected during air travel is low. The risk is greatest, though, when seated within about two seats/rows of a contagious individual. Walking around the cabin increases risk.
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Update on Early Pregnancy Loss Management
Early pregnancy failure typically is defined as an intrauterine pregnancy in the first trimester that is not viable, either because the gestational sac is empty or because the embryo or fetus has no cardiac activity. This article will discus the main options for the management of early pregnancy failure: expectant management, medical management with misoprostol, and surgical management. Women’s preferences should guide treatment decisions, given that all three options are medically safe.
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Interpregnancy Interval and Chances for Recurrent Miscarriage
Authors of a recent study surprisingly have shown that the best chances of avoiding another early pregnancy loss is to become pregnant within six months of a miscarriage.
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Can We Use Manual Vacuum Aspiration for Molar Pregnancies?
In this retrospective cohort study, manual vacuum aspiration in a hospital setting was equivalent to electric suction for uterine evacuation of molar pregnancy in terms of the risks of incomplete abortion and development of postmolar gestational trophoblastic disease.
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After the WHI: How Is Your Sex Life?
Women who discontinued systemic postmenopausal hormonal therapy following participation in the Women’s Health Initiative studies experienced an increase in vaginal and sexual symptoms.
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What Form of AV Block?
The long lead II rhythm strip shown in the figure was obtained from a hemodynamically stable patient. The rhythm was diagnosed as showing second-degree AV block, Mobitz Type II. Do you agree with that assessment?
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Clinical Briefs
In this section: comparing GLP-1 agonists; weighing two treatments for extended venous thromboembolism; and considering fracture risks possibly associated with inhaled corticosteroids.