Clinical
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Should Two-Dose Methotrexate Be the Standard of Care for Ectopic Pregnancy?
In this meta-analysis, the two-dose methotrexate treatment protocol was associated with higher odds of treatment success and a shorter treatment period compared to the single-dose protocol.
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Ripples From Original WHI Study Results Continue: Is This Appropriate?
Recommendations for menopausal hormone therapy were widely publicized and adopted following the original publication of the results of the Women’s Health Initiative and affected both initiation and continuation of estrogen therapy through at least 2013.
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Perimenopausal Depression
OB/GYNs strive to screen women for perinatal depression both in pregnancy and postpartum. Although depression frequently affects reproductive-age women, it is common in women throughout the lifespan. This article discusses depression in perimenopausal women.
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Brexanolone for Postpartum Depression: Promising, but Will It Deliver?
In two double-blind, randomized, placebo-controlled, Phase III trials of brexanolone, a new medicine for postpartum depression, researchers found a significant reduction in symptoms at 60 hours of infusion compared to placebo.
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Is There RBBB, Acute Ischemia, or Both?
The ECG in the figure was obtained from a 35-year-old man with a 20-year history of smoking. He presented to the ED with new-onset chest discomfort. He was hemodynamically stable at the time this tracing was obtained. How would one interpret his ECG? Is there right bundle branch block (RBBB)? Is there evidence of acute posterior ischemia or infarction?
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Sarecycline Tablets (Seysara)
Sarecycline is indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne in patients 9 years of age and older.
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Is Sanitizer Better Than Soap?
In day care settings, the implementation of hand hygiene programs reduced respiratory illness, absenteeism, and antibiotic use in children 0-3 years of age. Using hand sanitizer was more effective than washing with soap and water.
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Trends in Supplemental Vitamin D Intake
Researchers investigated the trends in daily supplemental vitamin D intake of ≥ 1,000 IU and ≥ 4,000 IU and found increasing use of vitamin D supplementation.
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Scientists Focus on Rapid Chlamydia Test
Just-released research findings indicate that a potential rapid chlamydia test delivers accurate results in about 30 minutes, which could make it possible for patients to be treated right away. Such point-of-care testing could help eliminate the need for follow-up appointments because patients would receive treatment at the time of diagnosis, say researchers.
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New Report Makes Case to Act Against Skyrocketing STDs
A new review by the National Academy of Public Administration makes a convincing case to act against skyrocketing sexually transmitted disease rates.