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Injectable Implant Focus of HIV Treatment/ Prevention Research

Researchers with the University of North Carolina at Chapel Hill and the Centers for Disease Control and Prevention are examining a new drug delivery system that uses dolutegravir, an established HIV drug, in a potential longacting treatment and prevention system. The system has been tested in animal models.

Research Strides May Offer Keys to Battling Gonorrhea

Researchers are investigating a rapid test that not only checks for gonorrhea infection, but also signals if a particular strain is antibiotic-resistant. On another front, scientists report that one dose of a developmental oral antibiotic proves effective in treating uncomplicated genital infections caused by gonorrhea.

Researchers Release Initial Results on Developmental Vaginal Ring

In an effort to provide both HIV/AIDS and unintended pregnancy protection, researchers have developed a vaginal ring containing the antiretroviral drug dapivirine and the contraceptive hormone levonorgestrel. Scientists have just released results of an initial clinical trial, noting no safety issues.

FDA Move Widens Approved Use of Human Papillomavirus Vaccine

The Food and Drug Administration has approved the use of the nine-valent human papillomavirus (HPV) vaccine in women and men ages 27-45. The Advisory Committee on Immunization Practices (ACIP) is scheduled to review further information at its February 2019 meeting, with a potential vote at that time. Insurance reimbursement often is based on ACIP guidance.

With Reclassification and New Name, Doors May Open for Internal Condom

The Food and Drug Administration has reclassified the female condom from a Class III device to a Class II device, putting it in the same category as the male condom.

What Does the Sinus P Look Like?

The ECG in the figure was obtained from a woman in her 50s who complained of intermittent chest discomfort in recent weeks. She was hemodynamically stable at the time this tracing was obtained. How might one interpret the ECG?

Sufentanil Sublingual Tablets (Dsuvia) CII

Sufentanil sublingual tablets are for adults with acute pain that is severe enough to require an opioid analgesic for which different treatments have proven insufficient.

Should Aspirin Be Used for Primary Prevention of Cardiovascular Events?

The conclusion from a series of groundbreaking studies is that primary prevention of cardiovascular disease and death by using daily low-dose aspirin is not recommended and should be reserved for those instances in which secondary prevention has been demonstrated to be effective in randomized, clinical trials.

Costs and Consequences of Chronic Pain Among U.S. Adults

Annually, chronic pain accounts for an estimated $560 billion in direct medical costs, lost productivity, and disability programs. Identifying populations at risk is the first step for developing targeted interventions for pain management.

Risk of Infective Endocarditis Revisited

In a comparison of patients with infective endocarditis (IE) and either bicuspid aortic valve (BAV) or mitral valve prolapse (MVP) vs. other IE patients at high or low-to-moderate risk of IE, BAV and MVP patients were more likely to exhibit viridans group streptococci infections of suspected odontogenic origin and cardiac complications at similar rates to high-risk patients.