Clinical
RSSArticles
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CRP and Reduction of Antibiotic Use in Acute Exacerbations of COPD
Point-of-care C-reactive protein testing can safely and effectively reduce antibiotic use in patients with acute exacerbations of COPD.
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Treating Infective Endocarditis in Moderate-Risk Patients
There are patients with a moderate risk of infective endocarditis who may warrant consideration of antibiotic prophylaxis.
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Calcitonin Gene-Related Peptide Targeting Therapies for Migraine
Two randomized clinical trials showed that calcitonin gene-related peptide targeting therapies are effective and safe for primary headache disorders.
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Size Matters Regarding Left Heart Valve Vegetations
An international registry study of left-sided valvular infective endocarditis patients revealed that large vegetations (> 10 mm) are associated with increased mortality at six months, but not if early surgery is performed.
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Blood Pressure Targets in the Elderly
The authors of a large population study found that reducing blood pressure to < 140/90 mmHg is associated with increased mortality, and mortality was highest in those with previous cardiovascular events and age > 80 years.
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Is There a Role for Surgery in Isolated Severe Tricuspid Regurgitation?
A retrospective single-center analysis of patients with isolated severe tricuspid regurgitation revealed no survival benefit from tricuspid surgery.
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Is It Safe to Stop Digoxin for Heart Failure?
In a large older patient heart failure with reduced ejection fraction hospitalizations database, the outcome of withdrawing digoxin vs. continuing digoxin was examined at 30 days and up to four years of follow-up. Withdrawing preadmission digoxin in hospital resulted in higher mortality at 30 days and more readmissions at six months, one year, and four years.
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Complete Revascularization After STEMI: Do We Finally Know the Answer?
In this largest trial to date, patients who were randomized to complete revascularization by percutaneous coronary intervention (PCI) following successful intervention at the time of ST-elevation myocardial infarction (STEMI) had a lower risk of cardiovascular death, myocardial infarction, and ischemia-driven revascularization vs. patients who underwent culprit lesion-only PCI.
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Molecular Analysis of Endometrial Cancer Corresponds With Outcomes in Young Women
SYNOPSIS: In this retrospective cohort study, researchers studied the prognosis and outcomes for young women with endometrial cancer and compared them according to tumor molecular classification.
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Association Between Self-Reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes
Cannabis use during pregnancy has become commonplace in states and countries (Canada) where it has been legalized for medical and/or recreational use. The authors of this study attempted to determine whether associations exist between self-reported prenatal cannabis use and maternal and perinatal outcomes.