Clinical
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IDWeek 2021: Skipping Along with Staphylococcus aureus
A single set of blood cultures may be inadequate to document clearance of Staphylococcus aureus bacteremia in some patients.
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IDWeek 2021: Gram-Negative Bacteremia: Are Follow-Up Blood Cultures Routinely Necessary?
A study of significantly immunocompromised patients with gram-negative bacteremia concluded that the routine use of follow-up blood cultures to document clearance is not warranted.
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IDWeek 2021: Baricitinib for COVID-19 Patients Receiving Invasive Mechanical Ventilation or ECMO
Baricitinib significantly reduced mortality in patients with COVID-19 receiving mechanical ventilation or extracorporeal membrane oxygenation.
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Prophylactic Probiotics Do Not Reduce the Risk for Developing Ventilator-Associated Pneumonia
A multicenter, randomized, placebo-controlled clinical trial revealed the use of prophylactic probiotics did not reduce the risk for developing ventilator-associated pneumonia or improve other outcomes for intensive care unit patients, compared to placebo.
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COVID-19 Vaccination and Myocarditis
Receipt of a COVID-19 mRNA vaccine is associated with a small but real risk of development of myocarditis, predominantly in young males. The vast majority of cases are mild, self-limited, and require no intervention.
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U.S. Advocacy Groups Declare National Emergency on Children’s Mental Health
Health professionals call on policymakers to address regulatory, financial, and technological challenges.
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Is There a Role for Intermediate-Dose Anticoagulation for Critically Ill COVID-19 Patients?
In a multicenter, randomized clinical trial of critically ill COVID-19 patients, intermediate-dose compared to standard-dose prophylactic anticoagulation did not result in significant differences in the rates of venous or arterial thrombosis, treatment with extracorporeal membrane oxygenation, or mortality within 30 days.
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Dexmedetomidine for Sedation in Patients Undergoing Mechanical Ventilation in the ICU
This special feature will focus on dexmedetomidine as a sedative for invasive mechanical ventilation in the ICU.
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Use of Ursodeoxycholic Acid in Pregnant Women with Obstetric Cholestasis
Ursodeoxycholic acid might be beneficial in reducing the risk of spontaneous preterm birth and meconium-stained amniotic fluid, but not stillbirths, in women with pregnancies complicated by obstetric cholestasis.
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Menopausal Hot Flashes: Can a Plant-Based Diet Provide Effective Treatment?
In this clinical trial, women randomized to a low-fat, vegan diet including one-half cup of cooked whole soybeans daily experienced a reduction in total hot flashes of 79% compared to 49% in the control group over 12 weeks of observation.