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  • Beta-Blockers and Dipyridamole Sestamibi Studies

    Although beta-blockers are known to reduce the sensitivity of exercise and dobutamine sestamibi SPECT imaging for the detection of coronary artery disease, little is known about their effects on vasodilator stress scintigraphy. Thus, Taillefer and colleagues studied 21 patients with catheter proven coronary artery disease during 3 different treatments on different days assigned in a random fashion.
  • Inheritance of Sudden Arrhythmic Death Syndrome

    A United Kingdom survey of sudden arrhythmic death syndrome in 32 victims aged 4-64 with normal hearts at autopsy and a negative toxicologic screening test evaluated first-degree relatives of these victims.
  • Catheter Ablation for Paroxysmal Atrial Fibrillation

    In this paper, Oral and colleagues compared 2 current ablation techniques in patients with paroxysmal atrial fibrillation.
  • ApoA-1 Milano: What’s the Fuss?

    This widely publicized small trial has catapulted the mutant form of ApoA-1 Milano into the limelight. Many investigators have been working with this interesting lipoprotein since it was discovered in the 1980s that 38 carriers from a small village in Northern Italy have very low HDL levels but very little vascular disease.
  • Sjögren Syndrome and Neuropathy

    What characteristics of a neuropathy make Sjögren syndrome the likely diagnosis?
  • Prions and Mesial Temporal Lobe Epilepsy: Not the Usual Suspects

    In an entirely novel observation, Walz and associates describe a cellular prion protein variant associated with hippocampal sclerosis that seems to be partially predictive of seizure-free outcome in patients undergoing surgery for medically refractory mesial temporal lobe epilepsy.
  • Smoking Increases Risk for Multiple Sclerosis

    In this epidemiologic analysis of 22,312 individuals living in Norway, a total of 87 reported having developed multiple sclerosis. The risk of developing multiple sclerosis was significantly higher among smokers than among never-smokers.
  • Cervical Artery Dissection: Another Economy Class Syndrome

    Economy class syndrome (ECS) refers to venous thromboembolic episodes among airline passengers who have remained immobile for long periods in cramped seating that impairs their circulation. Economy class passengers with little leg space are more likely to suffer such events than passengers in roomy first-class seats.
  • STD Quarterly: Syphilis rates climb for the second year

    Double up on your efforts to detect syphilis. Syphilis rates in the United States rose in 2002 for the second consecutive year, following a decade-long decline that resulted in an all-time low in 2000, according to new data from the Atlanta-based Centers for Disease Control and Prevention (CDC).1
  • Focus attention on bacterial vaginosis

    Your next patient says she has a vaginal discharge. A closer examination reveals a white, noninflammatory discharge that smoothly coats the vaginal walls. What is your next step?