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Six patients are the focus of this report defining the neuropathic side effects of thalidomide treatment in multiple myeloma. All patients developed a pure or predominant sensory polyneuropathy while on thalidomide. Thalidomide can induce an axonal sensory neuropathy or, infrequently, a ganglionopathy.
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Although infectious agents are not widely believed to be the primary cause of Alzheimers disease (AD), some evidence implicates certain neurotrophic viruses and bacteria as possible contributing factors. Canadian investigators Loeb and colleagues suggest that Chlamydia pneumonia infection might play a role in AD. They carried out a randomized, blinded, and placebo-controlled trial testing whether antichlamydial antibiotics (rifampin/doxycycline) could serve as a potential therapy for patients with mild-to-moderate AD.
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Although there are no approved medications to treat levodopa-induced dyskinesias, several strategies are commonly used. Reducing the interval and amount of each dose of levodopa, maximizing the dose
of dopamine agonists, and even liquefying the daily levodopa and giving it in small hourly increments are useful in selected patients. The present study evaluates clozapine in a double-blind, placebo-controlled trial as a treatment for levodopa-induced dyskinesias.
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The NIH has halted the estrogen-alone wing of the Womens Health Initiative a year before its scheduled end.
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Cholesterol and Coronary Heart Disease. Altern Med Alert 2004;7(4):S1-S2.
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Greenfield RH. Safety of niacin. Altern Med Alert 2004;7(4):48.
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Greenfield RH. Antibacterial soaps and infectious disease. Altern Med Alert 2004;7(4):47-48.
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Sasser H, Barringer T. Policosanol: A natural alternative for lipid management? Altern Med Alert 2004;7(4):37-41.
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Migraine and Subclinical Brain Lesions; Memantine Treatment in Alzheimer Disease; PPG in Type 2 DM