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With the muscle of an international cooperative group research network and expanded collaboration, confirmatory trials have been increasingly contemporaneously launched or provided important data in a timely fashion to help solidify important issues in the care of our patients.
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The use of CEE conferred protection against fracture without an increase in breast cancer but with an increased risk of hypertension, stroke, and venous thromboembolism.
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Includes the following Articles: Improved Blood Donor Screening for WNV, Azithromycin Failure as Prophylaxis or Treatment of Syphilis, United Kingdom Cracks Down on Potential Blood Donors and Human and Feline Sporotrichosis in Rio.
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This summary of selected abstracts from 3 meetings is published in multiple parts. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003. The Infectious Disease Society of America (IDSA) met in San Diego October 9-12, 2003. The American Society of Tropical Medicine and Hygiene met in Philadelphia December 3-7, 2003.
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Human metapneumovirus was the likely cause of 12% of all lower respiratory tract illnesses among a population of 2009 children studied from 1976 to 2001 presenting with acute respiratory symptoms. Clinical manifestations of metapneumovirus infection were bronchiolitis (59%), croup (18%), pneumonia (8%), and exacerbation of asthma (14%).
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When it comes to treating lipids in patients with heart disease, the mantra may be, The lower the LDL, the better. Data from the multicenter Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial indicate that aggressive reduction of atherogenic lipoproteins prevents progression of disease.
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In this article, Adams and Nelson integrate results from several disparate fields to advance the concept that autoimmune conditions resemble host vs graft disease and that the graft in many cases may be fetal or maternal cells that lodge in the host, namely the mother or fetus, respectively.
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Changes in screening, endocervical sampling, nomenclature, and improvements in treatment likely explain the increased in situ cervical SCC incidence in white and black women. Increasing AIS incidence over the past 20 years in white women has not yet translated into a decrease in invasive AC incidence.
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Hormonal replacement therapy after breast canceris It Safe? (HABITS) began in May 1997, to compare breast cancer survivors treated for at least 2 years with hormone therapy with treatment other than hormones. By September 2003, a total of 434 women had been randomized and, in December 2003, the steering committee of the HABITS study made the decision to stop the trial because there were 26 women in the treated group and 7 in the non-treated group with new breast cancer diagnoses.
