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  • Ideal Weight Gain in Pregnancy

    Last month an article was featured in the OB/GYN Clinical Alert from the October issue of Obstetrics & Gynecology. Since the issue was rich in good material, I will go back to it to review information pertaining to one of the most common questions asked of providers"How much weight should I gain in my pregnancy?"
  • Oral Contraceptives and Cervical Cancer

    The Collaborative Group on Epidemiological Studies of Cervical Cancer has combined and reanalyzed any relevant data from all epidemiological studies on the association between cervical carcinoma and the pattern of oral contraceptive use.
  • Special Feature: Biological Determinism: Time for a Paradigm Shift in Cancer Therapeutics?

    In the November 20th issue of the Journal of Clinical Oncology, two important articles appear, demonstrating the clinical impact of a novel therapeutic, bevacizumab, in women with recurrent ovarian cancer.
  • Pharmacology Watch: FDA Warnings Dominate Pharmaceutical News

    In this issue: FDA warnings for existing drugs dominate pharmaceutical news this month.
  • Clinical Briefs in Primary Care supplement

  • 'Tis the Season

    Neither antibiotics nor nasal steroids nor the combination of the two reduces the duration of acute sinusitis symptoms compared with placebo.
  • Intravenous Bisphosphonate and Facial Bones

    IV bisphosphonate treatment is associated with an increased risk of inflammation in the bones of the jaw and face.
  • Diagnosing Early Pancreatic Cancer

    Although pancreatic cancer growth is considered rapid, early recognition of resectable disease remains the best chance for long-term survival. It is possible that an early sign of evolving pancreatic neoplasm is glucose intolerance. In a series of 30 pancreatic cancer patients evaluated at the Mayo Clinic, CT scans obtained 6 months or more before the diagnosis revealed potentially resectable lesions in some, and this was notably true for those who had CT scans and new-onset diabetes several months before the diagnosis of pancreatic cancer. Thus, physicians evaluating adults with newly diagnosed diabetes should consider the possibility that the glucose intolerance is an accompaniment of early pancreatic neoplasia.
  • Sorafenib Tablets(Nexavar®)

    Sorafenib has been approved by the FDA forthe treatment of inoperable hepatocellular cancer. It is an oral multikinase inhibitor that was previously approved for advanced renal cell carcinoma. It is manufactured by Bayer HealthCare AG in Germany and marketed by Bayer Pharmaceuticals Corporation as Nexavar.
  • Clinical Briefs by Louis Kuritzky, MD

    Incidentalomas:It's All In Your Head, Skin Cancer Screening: Our Patients Want It!, and Bell's Palsy: Steroids, Acyclovir, Both, or Neither?