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Anticoagulation with vitamin k antagonists is the standard recommendation for patients with nonvalvular atrial fibrillation and risk factors for stroke. The benefits of warfarin in such patients have been well shown in many clinical trials. Therapy with warfarin, however, is often complicated by the dietary and drug interactions, so that even with frequent monitoring, precise control of the anticoagulation level is difficult.
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It remains debatable as to whether individuals who present with a non-ST-segment elevation MI (NSTEMI) or acute coronary syndrome (ACS) should be managed with a selective or elective invasive strategy vs an approach performing angiography in all patients.
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In this study, goldenberg and colleagues from the MADIT-II study analyzed risk factors for mortality in that trial. MADIT-II was a randomized trial of ICD versus conventional therapy, which included 1232 patients with documented previous myocardial infarctions who had an ejection fraction of ≤ 30%.
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Stop smoking drug Chantix rates stronger warning from FDA; Type 2 diabetes surgery on the way?; Vytorin study inconclusive; Influenza A virus found resistant to Tamiflu; FDA actions.
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The principal purpose of this clinical study was to evaluate the efficacy of gemcitabine relative to a clinical standard therapy, pegylated liposomal doxorubicin (PLD) in women with ovarian cancer relapsing within a year of primary treatments.
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Sentinel node localization and sampling has become a standard practice in the evaluation of regional nodal status for patients with breast cancer and cutaneous melanoma.
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One hundred and twenty subjects with symptoms of idiopathic detrusor overactivity (OAB) were recruited to evaluate the efficacy of reflexology compared to nonspecific foot massage.
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In a previous Clinical Alert, the risk of uterine rupture in patients attempting vaginal birth after cesarean sections (VBACs) was addressed when it appeared that there was a distinct downturn in the amount of VBACs being done in the USA.
