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Rehospitalization Common in Herpes Encephalitis
Herpes simplex encephalitis (HSE) is the most common cause of infectious encephalitis in the United States, accounting for around 30% of all causes of infectious encephalitis in the United States. With the advent of antiviral therapy and improved diagnostic measures, mortality and morbidity have improved over the past few decades, but patients remain at risk for long-term neurologic sequelae and even relapse.
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U.S. Endemic Fungal Infection Surveillance
In the United States in 2019, 29,061 cases of coccidioidomycosis were reported, as were 1,124 cases of histoplasmosis and 240 of blastomycosis.
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CDC Warning: Enterovirus-D68 Re-Emerging and Once Again Raising the Specter of Acute Flaccid Myelitis in Children
The Centers for Disease Control and Prevention is receiving increasing reports of pediatric infections with enterovirus-D68, which previously has been associated with the development of acute flaccid myelitis.
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Safety of Infliximab After Live Vaccines
Despite concerns about the use of infliximab for children with Kawasaki disease shortly after administration of live vaccines, retrospective reviews do not show any vaccine-related infections following subsequent infliximab use.
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Doxycycline Plus a Beta-Lactam for Treatment of Inpatients with Community-Acquired Pneumonia
In this retrospective study of an elderly male population hospitalized with community-acquired pneumonia, the combination of doxycycline with a beta-lactam was at least as effective as a respiratory fluoroquinolone or a combination of a beta-lactam with azithromycin.
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Cellular Tests Are Not Accurate for Diagnosing Lyme Disease
A prospective case-control study from the Netherlands evaluated three cellular tests for diagnosing Lyme disease. All three had low specificity compared to serological testing, leading to an unacceptably high number of false-positive results.
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Boosting with the New Bivalent COVID-19 Vaccines
The Centers for Disease Control and Prevention has made recommendations for the use of the newly approved bivalent COVID-19 booster vaccine.
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Antibiotic Resistance: We Were Doing Great and then COVID Happened
After improvement, antimicrobial resistance in the United States significantly increased.
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Self-Managed Abortion: A Guide to Harm Reduction and Patient-Centered Care
Even before the Dobbs v Jackson Women’s Health Organization decision, access to safe, legal abortion within the formal healthcare system was increasingly restricted. In this context, patients may turn to self-managed abortion (SMA). Clinicians should understand the course of SMA, including its overall safety, rare complications, and potential legal risks to patients.
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Utility of the Simplified Bishop Score in Trial of Labor After Cesarean Success
This study demonstrated that a higher likelihood of vaginal birth after cesarean was associated with a favorable simplified Bishop score on admission. This emphasizes the need for delaying patient counseling on the choice of trial of labor after cesarean delivery until the end of pregnancy to incorporate the cervical exam into decision-making.