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In Patients with Intracerebral Hemorrhage, Intensive Lowering of Blood Pressure Does Not Improve Outcome
intensive treatment of patients with intracerebral hemorrhage to achieve a target systolic blood pressure < 120 mmHg did not result in a lower rate of death or disability, but did result in an increased rate of renal adverse events.
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Stiff-Person Spectrum Disorder: What Can Antibody Profiles Tell Us?
This retrospective study of 121 patients with stiff-person spectrum disorder extensively examined antibody correlates of clinical features. Anti-GAD65 antibodies were highly associated with typical stiff-person syndrome, and anti-GlyR antibodies with SPS-plus. However, presence of anti-GAD antibodies predicted worse outcome than presence of antiGlyR antibodies, independent of clinical subtype.
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Structural and Functional Imaging ‘Phenotypes’ in Refractory Temporal Lobe Epilepsy Patients
Using high-resolution 3-T magnetic resonance imaging, temporal lobe epilepsy-hippocampal sclerosis showed significant preoperative ipsilateral volume loss, T2 hyperintensity, and mean diffusivity increases across all subfields, with the greatest effects seen anteriorly. However, temporal lobe epilepsy-gliosis showed increased volume in the dentate gyrus bilaterally, and more focal and subtle increases in T2 intensity and mean diffusivity.
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What is the End Game in Creutzfeldt-Jakob Disease Progression?
Cerebellar and psychiatric symptoms at diagnosis of Creutzfeldt-Jakob disease may portend a higher risk for more rapid development of akinetic mutism.
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For Migraine Pain, Green Light May Give Relief
Migraine-related photophobia appears to originate in cone-driven retinal pathways and is then mediated by thalamic neurons. Green light causes less stimulation than other colors.
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Guillain-Barré Syndrome in the Elderly
Guillain-Barré syndrome in the very old (> 80 years of age) results in more severe disease with poorer recovery.
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Ethics of Televised Prescription Drug Ads
There is widespread public support for removing televised prescription drug ads, according to a 2016 telephone survey of 1,006 U.S. adults.
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Only Half of Veterans with Advanced Cancer Receive Palliative Care, Says Study
Patients with advanced cancer should receive palliative care soon after diagnosis, according to the American Society of Clinical Oncology — but a recent study shows this is true for only half of veterans.
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Ethical Concerns if Patients are Abusive to Providers
Healthcare providers in the hospital setting are encountering increasing incidents of rude — and sometimes violent — patients and family.
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Study: Most Physicians Reported for Sexual Misconduct Aren’t Disciplined by Medical Boards
Most physicians reported by hospitals, medical societies, and malpractice insurers to the National Practitioner Data Bank for sexual misconduct have never been disciplined by their state medical board for that behavior, a recent study found.