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An IRB dedicated to handling cancer research has shown benefits in efficiency and expertise when such a specialty IRB model is employed.
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Researchers say there need to be more clinical trials examining the safety and effectiveness of pain medications used with children, which are too often administered based on information from adult trials.
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Current American College of Cardiology/ American Heart Association (ACC/AHA) Guidelines recommend withholding non-steroidal anti-inflammatory drugs (NSAIDs) from patients who have suffered a myocardial infarction (MI) and substitution of another analgesic such as acetaminophen. If NSAID therapy is unavoidable, the guidelines recommend the shortest duration possible.
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This single-center, double-blind, randomized, controlled crossover trial demonstrated that administration of 100% oxygen to stable patients with obesity hypoventilation syndrome leads to decreased minute ventilation, increasing dead-space to tidal volume ratio, and worsening hypercapnia.
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With the advent of new vaccines, the incidence of bacterial meningitis has declined, particularly in children, but the mortality rate has remained the same.
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Proton pump inhibitor use in clopidogrel-treated post-percutaneous coronary intervention patients was not associated with an increased risk of all-cause death, nonfatal myocardial infarction, repeat revascularization, or major adverse cardiovascular events.
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