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When Do Combined Oral Contraceptives Start Working After Ulipristal Acetate Emergency Contraception?
In this randomized, controlled trial of the effects of combined oral contraceptives on ovarian activity after taking ulipristal acetate, investigators found that some women needed up to 14 days to achieve ovarian quiescence. Therefore, abstinence or backup contraception should be used during that time.
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Good News for a Change: No Association of Hormonal Replacement Therapy with Breast Cancer Before Age 50
Using data from the Two Sister Study, investigators found no association of past combined hormone replacement therapy with young-onset (before age 50) breast cancer, and a protective effect with estrogen-only therapy.
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Handheld Ultrasound for Assessing Fetal Size
A recent study has shown abdominal circumference assessments with a portable handheld ultrasound machine to be superior to standard fundal height measurements in the prediction of small for gestational age and large for gestational age fetuses in utero and infants at birth.
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Using Critical Care Ultrasonography to Diagnose the Etiology of Acute Respiratory Failure
Thoracic ultrasound and limited echocardiography may be useful to help differentiate the causes of acute hypoxic respiratory failure in the ICU.
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Optimal Duration of Anticoagulation for Unprovoked Pulmonary Embolism
Treatment for 24 months with oral anticoagulation for unprovoked, first-time pulmonary embolism was superior to treatment for 6 months only.
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The Complex Intersection of Critical and Palliative Care
Ventilator withdrawal with expected death is now considered an ethically and morally acceptable practice. Here's what you need to know.
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Clinical Briefs
In this section: Reconsidering the value of oral nutritional supplementation in patients admitted for COPD; recognizing a relationship between asthma and obesity; and weighing the benefits of sound stimulation in Alzheimer's patients.
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Eluxadoline Tablets (Viberzi) and Rifaximin (Xifaxan) Tablets
Both drugs appear to provide modest benefit in irritable bowel syndrome with diarrhea.
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Statin Use and Cognitive Effects: Not a Brain Drain
A meta-analysis of data from more than 28,000 patients enrolled in 18 randomized, placebo-controlled trials of statin therapy failed to show a causal relationship between treatment and adverse neurocognitive effects for patients with and without cognitive impairment.
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Prostate Cancer and Smoking: One More Reason to Trash the Tobacco
Study showed that following prostatectomy for cancer, smokers and ex-smokers had a higher risk of recurrence.