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In this small, uncontrolled trial, autologous stem cell transplantation appeared to be efficacious for the treatment of patients with refractory CIDP.
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Myoclonus-dystonia is characterized by specific neurophysiological dysfunctions that appear to be different from the ones seen in other dystonias.
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A pooled analysis of four clinical trials concluded that treatment with onabotulinumtoxinA at doses of 75-260 U administered every 12 weeks for up to five treatment cycles was efficacious, safe, and well tolerated for the prophylaxis of headache in adults with chronic migraine.
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Vitamin D3 supplementation in patients with persistent asthma and low serum vitamin D (25(OH)D) did not show improvement in the clinical efficacy of inhaled corticosteroids.
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A meta-analysis and systematic review found vitamin C supplementation improved endothelial function in patients with diabetes, atherosclerosis, and heart failure.
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Lipoic acid (LA) is a supplement that has much current interest for a variety of therapeutic reasons. Historically, its use as an antioxidant has been known for a long period of time.
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A study comparing experienced meditators and non-meditators found that the meditators had more favorable changes in some biochemical markers of stress-linked cell damage and inflammation. Those in both groups who responded more effectively to a stressful stimulus also showed somewhat better marker levels than those who responded less well.
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In this large prospective study of trauma patients, the most important factor associated with post-traumatic seizures was the presence of alcohol intoxication.
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A large, multicenter clinical trial that compared protocol-based care to usual care for patients presenting to emergency departments with early sepsis and septic shock found no differences in clinical outcomes. However, early recognition and therapy was beneficial and should be the standard of care.
