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Clinicians are becoming more attuned to the many complications of influenza, particularly with the high morbidity and mortality seen with H5N1 strains spreading around the world.
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In This Issue: FDA drug approval to change? Urinary incontinence in women; how metabolism of certain drugs can be predicted by genetic analysis; bowel preps may compromise renal function especially in the elderly according to a new study; FDA Actions.
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Eight hiv-infected patients (mean CD4+ t cell count 622 cells/uL) who had been receiving effective HAART for an average of 8.4 years were included in this study. PBMCs were obtained by leukapheresis and endoscopic terminal ileum biopsies were performed to obtain samples of Gut-Associated Lymphoid Tissue (GALT).
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In 1985, the newly fda-approved antimicrobial agent, Primaxin® (imipenem/cilastatin), introduced a new class of drugs known as carbapenems. This new class provided benefits as well as unwanted side effects. Carbapenems work similarly to other â-lactam antibiotics, but with substantially broader-spectrum of activity and better penetration into bacterial cell walls to prevent synthesis.
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Trauma in wartime is especially high risk given the nature of the injuries, the high risk of infection, and the limited access to optimal medical care.
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A multicenter, randomized, double-blind, placebo-controlled trial of hydrocortisone replacement in patients with septic shock found no mortality benefit in those patients with inadequate baseline response to corticotropin stimulation.
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There is an increased risk of future cancer as a consequence of performing repeated CT scans, and the younger the patient at the time of scanning, the greater the subsequent risk.
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Exposure to small turtles has lead to a multistate outbreak of Salmonella paratyphi B var. Java infections. This MMWR report summarizes the epidemiologic and laboratory investigation conducted by CDC and state and local health departments since the first reported illness on 5/4/07.
