-
-
The term thrombocytopenia refers to platelet counts < 150,000/microL, with severe thrombocytopenia defined as a count < 50,000/microL.
-
Mean daily doses of up to 40 mg of prednisone equivalents and lengthy ICU stays were associated with impaired physical outcomes in patients who survived acute lung injury.
-
In this retrospective study of extubation outcomes in five ICUs at a single medical center, patients extubated at night had no increase in adverse events and their mortality rates and lengths of ICU stay were lower.
-
The IRB at Grand Valley State University in Allendale, MI, uses a matrix that clarifies how IRB members and staff might describe various potential harms at four levels, from no more than minimal risk to high risk.
-
Technology advances have driven increased interest in molecular studies involving tissue analyses. As a result, biotech firms increasingly are asking scientists to sell human tissues for study by outside enterprises.
-
The Presidential Commission for the Study of Bioethical Issues May 2014 report, Gray Matters: Integrative Approaches for Neuroscience, Ethics, and Society, includes recommendations for institutions and individuals engaged in neuroscience research.
-
Even as multicenter studies with central IRB reviews gain traction, some IRBs are still hesitant to join in. However, coordinating a multisite study among several IRBs within the same university system can be a time and paperwork hassle for both principal investigators and IRBs and could make previously reluctant IRBs consider a new central reliance agreement.
-
Evaluating research risk requires understanding a variety of potential harms and their nuanced impact. IRBs might find it useful to have a matrix to help explore each potential harm.
-
As IRB offices gear up for a busy academic research year, its a good idea to dust off IRB templates, checklists, and other tools to revise, improve, and adapt to technology and other changes.
