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In this issue: Fractures and bisphosphonate therapy, warfarin anticoagulation and influenza vaccine and cotrimoxazole, antiplatelet therapy with clopidogrel and aspirin, FDA Actions.
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Casey and colleagues compared the effects on pain, level of consciousness, and vital signs of 2 different doses of remifentanil and placebo for removal of chest drains after cardiac surgery in 60 patients.
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Raurich and colleagues studied 80 patients with acute respiratory distress syndrome (ARDS) to determine whether the alveolar dead-space fraction (VD/VT, the proportion of each breath that does not participate in gas exchange) was a predictor of ultimate survival. The patients were ages 18 years or older, acutely ill in the investigators' ICU, and met the current international diagnostic criteria for ARDS.
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This study from a surgical ICU in a french university hospital sought to determine the effect on catheterization duration of a daily reminder notifying physicians that the patient had a central venous catheter (CVC) or urinary tract catheter (UTC) and asking whether there was continued need for that catheter.
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This is a small U.S.-based clinical trial of 23 adolescent women (ages 14-18) randomized to levonorgestrel-releasing vs Copper T intrauterine device (IUD).
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The management of a patient with suspected fetal macrosomia remains an enigma. Not being able to come up with a consistent plan of management for macrosomia is compounded by our inability to reliably predict it.
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Depot medroxyprogesterone acetate (DMPA) is a highly effective progestin-only contraceptive that is widely used by adolescents. DMPA is also associated with suppression of ovarian production of estradiol, and with a decrease in bone density in some users.
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The primary objective of this retrospective study was to estimate the incidence of genetic counseling referral for ovarian cancer patients who were at high risk for carrying a mutation in BRCA1 or BRCA2.
