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  • Anemia and Brain Function in Elderly Lung Cancer Patients

    Chemotherapy-related anemia is associated with impairment of functional status and cognitive functions. In elderly cancer patients anemia correction or maintenance could be useful to preserve functional independency and protect from mental decay. However, the study results need to be confirmed on a larger series of patients within a controlled clinical trial.
  • Patients with Alzheimer’s Disease Receive Less Aggressive Treatment for Breast Cancer

    In a pattern-of-care analysis performed by linking the SEER database with Medicare claims data, it was found that, matched for age, breast cancer patients who had coexisting Alzheimers disease were less likely to have surgery, radiation or chemotherapy than those without Alzheimers disease.
  • Oral Fludarabine for Indolent NHL: A Phase II Trial

    In a phase II study conducted in Japan, oral fludarabine phosphate administered to patients with B-cell non-Hodgkins lymphoma was shown to have an overall response rate of 65%, but with significant, albeit manageable, hematologic toxicity. Oral administration of this drug may prove a convenient alternative to the current regimens which call for several clinic or infusion center visits in the week of therapy.
  • Intraperitoneal Chemotherapy: Coming of Age?

    As compared with intravenous paclitaxel plus cisplatin, intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel improves survival in patients with optimally debulked stage III ovarian cancer.
  • Clinical Briefs in Primary Care supplement

  • Pharmacology Watch

    Letrozole for Postmenopausal Women with Breast Cancer; Do Antidepressants Increase Risk of Suicide?; Can Viagra Improve Heart Function?; Can Tamoxifen Increase Your Height?; A Dramatic Increase of Clostridium difficile; FDA Actions
  • Full February 2006 issue in PDF

  • Shaky Evidence for an Old Technique

    The use of a steroid ointment following a 20-minute soak may relieve chronic skin conditions.
  • Is LDL Cholesterol the Best CHD Lipid Marker?

    Illnesses produced by vascular diseases are far and away the most common cause of death in the developed world and, amazingly enough, will become the leading cause of death even in the developing world by 2020.1 Identifying individuals at increased risk of coronary artery heart disease (CHD) is critical in preventing CHD and, in 2002, the Adult Treatment Panel III (ATP III)2 reaffirmed its previous position by concluding that low-density lipoprotein cholesterol (LDL-C) would remain the cornerstone of lipid management.
  • Forgotten Hazards of Sedatives

    This case series and prospective observational study describe propylene glycol toxicity in patients receiving IV benzodiazepines. The authors estimate the incidence of this important but unrecognized complication to be 19%.