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In this meta-analysis, Quiroz and colleagues attempted to identify all English-language reports published since 1990 that included at least three months of follow-up in patients clinically suspected of having pulmonary thromboembolism (PTE), whose computed tomography (CT) angiograms were negative, and who did not receive anticoagulant therapy.
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Appendicitis is a serious diagnosis with the potential for catastrophic outcomes in any age group, but especially in the young child. Although the clinician may have this diagnosis in the differential for select patient populations, this article highlights the clinical scenarios when the clinician should consider the diagnosis in a child.
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An increased dietary intake of folate reduces the risk of developing AD.
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Depression and anxiety in Parkinson's disease might be associated with a specific loss of dopamine and noradrenaline innervation in the limbic system.
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In a randomized trial of neurosurgical clipping versus endovascular coiling for ruptured intracranial aneurysms, endovascular coiling was more likely to result in independent survival at 1 year.
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Successful treatment of SDB, which is frequently associated with chronic sleepwalking, controlled the syndrome in young adults.
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Dopamine neuronal replacement cell therapy can be beneficial for patients with advanced disease, and that changing technical approaches could have a favorable impact on efficacy and adverse events following neural transplantation.
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Introduction of HAART has dramatically modified the natural history of HIV disease by controlling viral replication, but, in turn, lengthening of the survival of HIV-infected individuals has been associated with an increasing prevalence of iatrogenic conditions.
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More recent trials, and meta-analyses of all trials, have shown a reduction in death and myocardial infarction (MI) with a routine invasive strategy vs an ischemia or symptom-driven invasive strategy over 6-24 months for patients with non-ST elevation (E) acute coronary syndrome (ACS). However, an increase in death during the initial hospitalization in the routine invasive arm makes long-term outcome data important. Thus, the British Heart Foundation RITA 3 trial 5-year data are of interest.
