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Clinical trial site investigators and others involved in contract negotiations can improve their negotiation techniques by following six simple steps, an expert says.
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It's a more competitive, tougher clinical research (CR) world out there when it comes to sites keeping track of metrics and creating study budgets.
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Clinical trial sites can improve their budgeting process by developing a good study feasibility process. Sites might use a feasibility tool to help prevent the site from underestimating a clinical trial site's costs for any particular protocol.
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Research investigators need to find a balance between giving enough information about potential subjects in study advertisements to giving too little information and being inundated with unnecessary calls.
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A well-conceived electronic database can make it possible for a quality improvement (QI) department to quickly identify and act on noncompliance trends.
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Laboratory studies and clinical data support the concept that prolonged mechanical ventilation (PMV) can induce or worsen lung injury, via activation of inflammatory mediators and/or microvascular fibrin deposition, processes that may be ameliorated by heparin.
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In this study from the Mayo Clinic in Rochester, MN, Herasevich et al tested an electronic algorithm that incorporated patient characteristics and ventilator data and notified clinicians immediately when potentially injurious ventilator settings were being used.
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Due to its lack of cardiovascular side effects, the short-acting non-barbiturate sedative, etomidate, has been one of the primary agents used to sedate hypotensive patients during rapid-sequence intubation (RSI).
