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International HIV vaccine trials underway in resource-poor settings provide good examples of how clinical research (CR) can be done in both ethical and culturally-sensitive ways despite a wide variety of obstacles.
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Investigators studying "elite suppressors," this unique group of HIV-infected individuals who can ward off illness from HIV for years or even decades, have found clues that might lead to powerful new treatments.
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HIV research increasingly points to a connection between CD8 T cells and suppressed virus, but precisely how this works remains a mystery.
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Elite suppressors are that 1% or fewer of HIV patients who do not develop signs of disease progression despite living for years without treatment.
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Men and women infected with HIV dramtically reduced the risk of transmitting the virus to their sexual partners through initiation of oral antiretroviral therapy (ART), according to findings from a large multinational clinical study conducted by the HIV Prevention Trials Network (HPTN).
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Can the informed consent process actually provide too much information? That's the contention of HIV researcher Susan Allen, MD, MPH, who points to a recent study she tried to conduct in Zambia of participants' knowledge about contraceptive options.
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The Food and Drug Administration is proposing to amend its regulations to expand the scope of clinical investigator disqualification.
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The U.S. Department of Health and Human Services' recently published proposed rule (42 CFR 425) for Accountable Care Organizations (ACOs) could result in some positive changes for the health care industry, but there are a few problems that should be corrected, an expert says.
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Some hospitals have been focusing more on care transition issues in anticipation of the advent of accountable care organizations (ACOs) or just because it's a way to improve both quality and efficiency in health care.
