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It comes as no surprise that when patients do not take their blood pressure (BP) medication, a lapse in BP control is anticipated. On the other hand, when a patient presents with an elevated BP and acknowledges omitted doses, it is difficult to be sure whether the observed elevation in BP is solely due to recent omissions, an underlying worsening of BP (requiring an augmentation rather than just simple restoration of treatment), rebound BP elevation, or some combination of these elements.
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The medical literature is rife with information on the trends of various infectious diseases. Much of this begins with the diagnosis made and helps us connect the diagnosis to a preferred regimen of antimicrobials or antivirals. The real detective work starts before this. Our tools are constant vigilance for subtle clues in the history and physical examination, some nonspecific laboratory tests (for example white blood cell [WBC] count or lactate), and a high level of suspicion for infection.
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No one asks large pharmaceutical companies to develop and market new drugs as a nonprofit venture. So why would anyone expect clinical research sites to operate at a loss?
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Clinical research technology continues to evolve at a pace thats difficult to fathom. Everything from study recruitment to budgeting to operations are changing and evolving because of technological advances.
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Theres a resounding cry in the research industry for better technological integration and clinical research collaboration, but the movement in this direction has been very slow, an expert says.
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Budgeting is a complicated process, but you can make it work well by following thorough and well-organized, step-by-step strategies.
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A major research organization in the Northeast successfully uses an electronic data capture (EDC) system with hundreds of clinical trials each year.
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