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Trying to recruit people with medical conditions for research while maintaining their confidentiality can be a challenging task.
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When the IRB faced a regulatory crisis period in the late 1990s, research institutions responded by putting more resources into human subjects protection and compliance, and the IRB world responded with the introduction in 2000 of the Certified IRB Professional (CIP) examination by Public Responsibility In Medicine and Research (PRIM&R) of Boston, MA.
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The Certified IRB Professional (CIP) credential has gained considerable respect in its 10 years of existence, especially among research institutions seeking employees who have passed the CIP exam or who are willing to take the test as soon as they qualify.
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Many clinicians are reluctant to give low-dose aspirin (ldasa) to pregnant women for the prevention of preeclampsia. This reluctance is not based on a fear of potential risk, but on inconsistent study results regarding the efficacy of ASA.
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Secondary recurrent miscarriage (defined as three or more pregnancy losses at < 20 weeks occurring in a women with a least one pregnancy carried beyond 20 weeks) may be explained by a chromosomal abnormality or be "unexplained" (idiopathic).
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The "Caprisa 004" trial was a randomized double-blind controlled trial of 1085 sexually active, HIV-negative, high-risk women in South Africa over 2.5 years (889 women were included in the final analysis).
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Previous investigation of cervical cancer biology has revealed a dependence on VEGF, among other factors, for growth and metastases.
