-
Serum prostate-specific antigen (PSA) testing is frequently used in early detection programs for prostate cancer. While PSA testing has resulted in an increase in prostate cancer detection, its routine use has been questioned because of a lack of specificity. The objective of this study was to determine whether year-to-year fluctuations in prostate-specific antigen levels are due to natural variation and render a single PSA test result unreliable.
-
Jneid and associates critically analyzed the results of the Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study and several other antiplatelet trials to provide guidance to the physician regarding the use of aspirin and/or clopidogrel in patients with ACS.
-
-
The rapid immunochromatographic urine test Binax NOW was found to be a valuable, sensitive, and rapid test for diagnosing pneumococcal pneumonia even after antibiotic therapy had been started.
-
Drug discovery activities have yielded agents effective against a novel target in staphylococci.
-
Prophylactic administration of immunoglobin failed to demonstrate any benefit among recipients of an allogeneic hematopoietic stem cell transplant from HLA-identical sibling donors.
-
The yeast Candida versatilis was isolated from 10 blood cultures from neonates drawn over a period of 10 days.
-
A study of children with perinatally acquired hepatitis C infection followed for an average of 4.8 years showed persistent HCV infection in 81%, with liver disease that was mild. HCV genotype 3 was associated with a higher rate of loss of HCV RNA and normalization of ALT by 30 months of age.
-
The chimpanzee simian immunodeficiency virus, the virus from which HIV-1 originated, arose as the result of recombination between retroviruses of 2 smaller primates that may serve as a food source for the chimp.
-
Four patients treated with levofloxacin for pneumococcal pneumonia had one or more relapses with levofloxacin-resistant isolates. In 5 of 6 relapses, the infecting strain was identical to the initial levofloxacin-susceptible strain by DNA typing.
