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Synopsis: The clinical value of single-agent trastuzumab in recurrent ovarian cancer is limited by the low frequency of HER2 overexpression and low rate of objective response among patients with HER2 overexpression.
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Synopsis: Acute oral administration of 50 mg and 100 mg of androstenedione to postmenopausal women increases serum testosterone and estrone but not estradiol.
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Synopsis: Postpartum fever after cesarean delivery is associated with an increased risk of uterine rupture during a subsequent trial of labor.
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In emerging findings that will fuel more debate about immunizing U.S. health care workers for smallpox, a similar program in Israel has resulted in four hospitalizations including the immunocompromised wife of a vaccinee, Bioterrorism Watch has learned.
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With its smallpox immunization plan now under way in the nations hospitals, the Centers for Disease Control and Prevention (CDC) must decide how many adverse reactions and deaths are acceptable before modifying or halting the program, told a special smallpox review panel formed at the Institute of Medicine (IOM) in Washington, DC.
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Harsh lessons learned from the governments forced anthrax vaccination campaign in the military include poor communication, driving people out of the service, and massive underreporting of adverse reactions among those immunized, according to a report by the General Accounting Office (GAO).
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Health care workers receiving their first lifetime vaccination for smallpox only should be stuck three times with the bifurcated immunization needle not the 15 skin pricks previously recommended by the Centers for Disease Control and Prevention (CDC).
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The Joint Commission on Accreditation of Healthcare Organizations has sent out a sentinel alert to all accredited facilities calling for them to report fatal nosocomial infections. The request for data has raised concerns among infection control professionals, who argue that ascribing deaths to infections is a complex matter confounded by underlying illness and a host of other variables.
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West Nile virus is emerging as a new threat to laboratory workers as its presence grows in the United States. Infection control precautions should be reemphasized in light of two occupational cases of West Nile virus infection in research laboratorians, the Centers for Disease Control and Prevention (CDC) emphasizes.
