Clinical Cardiology Alert
View Issues
-
Artificial Intelligence ECG Analysis to Rule Out Acute Myocardial Infarction
A large Korean study of an artificial intelligence electrocardiogram (ECG) interpretation algorithm for identifying patients with acute myocardial infarction showed a high degree of accuracy for diagnosing acute myocardial infarction and identifying patients at risk for 30-day major adverse cardiac events in an emergency department setting, which was similar or superior to standard risk stratification methods.
-
Shortened DAPT Followed by Reduced-Dose Prasugrel Monotherapy Notches a Win in ACS Patients
In this study of acute coronary syndrome (ACS) patients, one month of dual antiplatelet therapy (DAPT) followed by reduced-dose prasugrel monotherapy led to a reduction in major bleeding events compared to 12 months of DAPT, without a corresponding increase in ischemic events.
-
CT Coronary Artery Calcium Progression After an Initial Score of Zero
A large Korean study of asymptomatic subjects undergoing more than one computed tomography (CT) coronary calcium scoring scan as part of an employment-based health screening has shown that most had scores of 0, and that during a maximum follow-up of 12 years, the majority stayed at 0 on a repeat scan. Also, in those with a coronary artery calcium score of 0 initially, clinically significant scores (> 100) were only found in 4% of scans at 10-year follow-up.
-
New Injectable Cholesterol-Lowering Drug Trial
A comparison of inclisiran therapy to placebo and ezetimibe therapy over six months in primary prevention patients at low risk of atherosclerotic cardiovascular disease and not taking lipid-lowering therapy has shown that inclisiran subcutaneously every six months reduces low-density lipoprotein cholesterol more than ezetimibe and is comparable to the reported results of high-dose statins taken daily.
-
Is Sex Still an Important Variable in Stroke Risk with Atrial Fibrillation?
An analysis of a very large database of patients with recent-onset atrial fibrillation has shown that whether sex was included in the formulas to predict thromboembolic risk and guide the use of oral anticoagulants probably is not as important as it was decades ago.