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Using the SEER database, data for patients with adenocarcinoma of the pancreas diagnosed in 1995-2005 were analyzed for the occurrence of suicide. As expected, the rates were higher than those reported for the general population, but among men, particularly those who were recovering from surgery, the mortality rate from suicide was 10 times greater than that of the general population. Care providers should be aware of this heightened risk and intervene as possible.
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Among three distinct cohorts of lung cancer patients and matched controls (without tumor), the authors present data on the capacity for an assay that detects antibody to tumor-associated antigens to discriminate those with lung cancer and those without. Using a panel of six antigens, they found their assay to have sensitivity/specificity of approximately 40%/90%. If confirmed in an independent prospective study, such screening may be a very effective adjunct to imaging studies in the early recognition of lung cancer.
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The optimal standard salvage therapy for relapsed or refractory AML remains undetermined. The authors retrospectively compared two regimens at a single institution: CLAG (cladribine, high-dose cytarabine, and G-CSF) with MEC (mitoxantrone, etoposide, and cytarabine). These observational data without adjustment suggest CLAG may be superior to MEC. Nevertheless, outcomes for relapsed or refractory AML remain poor and clinical trials should be entertained when available.
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Apixaban and rivaroxaban near approval for nonvalvular atrial fibrillation; fidaxomicin for C. difficile infections; guideline for intensive insulin therapy; and FDA Actions.
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Dosages based on the color-coded Broselow Pediatric Emergency tape will soon be displayed on a large LCD monitor for all ED staff to see, says Andre A. Muelenaer Jr., part of the product's developmental team and an associate professor of pediatrics at the Virginia Tech Carilion School of Medicine in Roanoke.
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Exertional heat-related injuries are on the rise in EDs, with an estimated 54,000 patients treated over a 10-year period a 133% increase that was not linked to increased seasonal temperatures, according to a new study.
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"Normal-looking" asthma patients, whose condition is poorly controlled with treatment, or patients who are not compliant with treatment, may show up in your ED after weeks of deteriorating gradually, warns Anissa Washington, RN, BSN, ED nurse at St. John's Mercy Medical Center in St. Louis, MO.
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Smoking, lung diseases, and chest X-ray abnormalities may result in your ED patient being diagnosed with bronchitis, flu, pleurisy, costochondritis, and upper respiratory infection, when he or she actually has pneumonia, says Carrie April, RN, BSN, an ED nurse at St. John's Mercy Medical Center in St. Louis, MO.
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Editor's Note: This is a two-part series on medication safety for inpatients being held in the ED. This month, we give strategies to avoid missed dosages; next month, we'll cover how ED nurses can reduce errors with inpatient medications.
