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Castleman Disease, a rare lymphoproliferative disorder characterized by fever, lymphadenopathy, splenomegaly, high sedimentation rates, and polyclonal hypergammaglobulinemia, is being seen with increasing frequency in HIV-positive persons.
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Refugees resettling to the United States and other developed countries frequently suffer from infectious diseases, and can pose diagnostic or therapeutic dilemmas for health care providers in their new homes.
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This multicenter, randomized, placebo-controlled trial of a synthetic GHRH analogue, tesamorelin (1-44 amino acids from the amino terminal of GHRH with a trans-3-hexenoyl group added to the amino terminal to increase the half-life over native GHRH), randomized 412 patients (86% male) to daily subcutaneous tesamorelin vs placebo for 26 weeks.
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Sixty-one hospitals in 28 countries participated in a prospective cohort study of hospitalized patients with definite endocarditis.
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The diagnosis of malaria has traditionally relied upon microscopy. However, microscopic diagnosis is labor intensive and somewhat subjective, and assurance of quality standards can be difficult at best.
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In this issue: Rosiglitazone (Avandia) implicated in yet another study; Prilosec and Nexium not associated with cardiac events; Anastrozole (Arimidex) shown more effective than tamoxifen for treatment of early-stage breast cancer; antibiotics show no effect on sinusitis; FDA actions.
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At the 56th annual meeting of the American Society of Tropical Medicine and Hygiene held Nov. 4-8, 2007, in Philadelphia, Paul Arguin, MD, Chief of the Domestic Malaria Unit at the Centers for Disease Control and Prevention, presented the Malaria Prevention Update from the CDC.
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A clinical pre-meeting course at the 56th annual meeting at ASTMH was conducted and entitled, Chagas' Disease: (American Trypanosomiasis): No Longer an Exotic Disease.
