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In daily clinical practice, OAC was only given to a minority (30%) of AMI patients with AF, despite the fact that OAC was associated with a 29% relative and 7% absolute reduction in 1-year mortality after adjustment for confounding variables. The results emphasize the importance of OAC treatment for AF after AMI.
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Oral amiodarone prophylaxis of atrial tachyarrhythmias after cardiac surgery is effective and well tolerated.
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There is a wide variation in presentation and course of ARVD patients, which can likely be explained by the genetic heterogeneity of the disease.
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The high rates of acute vascular events outside the coronary arterial territory and the steep rise in event rates with age in all territories have implications for prevention strategies, clinical trial design, and the targeting of funds for service provision and research.
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Fenofibrate did not significantly reduce the risk of the primary outcome of coronary death or non-fatal MI. It did reduce total cardiovascular events, mainly due to fewer non-fatal myocardial infarctions and revascularizations.
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When study data were used to perform a formal analysis of costs associated with use of erythropoietin, the total cost to avoid one transfusion-related adverse event was $4.7 million.
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Both intra-abdominal hypertension and evidence for its adverse physiologic effects were common in this retrospective series of ICU patients with severe acute pancreatitis, although there was no association with mortality, and 3 of 4 patients subjected to decompressive laparotomy died.
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In a randomized, controlled trial, patients with stroke or head injury who required mechanical ventilation were less likely to develop ventilator-associated pneumonia if they underwent early percutaneous gastrostomy for nutritional support than if they continued to be fed via nasogastric tube.
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Airway Management is an integral and frequent component of care of the critically ill.
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This prospective 10-year study of 7356 patients with ST-elevation MI who presented in cardiogenic shock showed once again that early mechanical revascularization (as recommended by current guidelines) substantially increases survival; it also suggests that adherence to the guidelines needs to be further improved.
